Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos |
| Upregulated in class | transDMpreB |
| GeneSet | INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE |
| Enrichment Score (ES) | 0.67676 |
| Normalized Enrichment Score (NES) | 1.6105542 |
| Nominal p-value | 0.009029346 |
| FDR q-value | 0.21871924 |
| FWER p-Value | 0.855 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ITPR3 | 9195 | 31 | 2.936 | 0.1105 | Yes | ||
| 2 | RAC2 | 22217 | 117 | 2.387 | 0.1971 | Yes | ||
| 3 | BTK | 24061 | 118 | 2.378 | 0.2880 | Yes | ||
| 4 | ITPR1 | 17341 | 285 | 1.959 | 0.3539 | Yes | ||
| 5 | SYK | 21636 | 513 | 1.619 | 0.4035 | Yes | ||
| 6 | TYK2 | 12058 19215 | 563 | 1.543 | 0.4599 | Yes | ||
| 7 | MAP2K1 | 19082 | 767 | 1.285 | 0.4980 | Yes | ||
| 8 | CSK | 8805 | 940 | 1.117 | 0.5314 | Yes | ||
| 9 | JAK1 | 15827 | 1249 | 0.894 | 0.5490 | Yes | ||
| 10 | JAK3 | 9198 4936 | 1299 | 0.858 | 0.5791 | Yes | ||
| 11 | VAV1 | 23173 | 1340 | 0.841 | 0.6091 | Yes | ||
| 12 | TEC | 16514 | 1394 | 0.805 | 0.6370 | Yes | ||
| 13 | PTK2 | 22271 | 1498 | 0.741 | 0.6598 | Yes | ||
| 14 | MAP2K2 | 19933 | 1669 | 0.648 | 0.6754 | Yes | ||
| 15 | FOS | 21202 | 2168 | 0.392 | 0.6636 | Yes | ||
| 16 | PTK2B | 21776 | 2197 | 0.385 | 0.6768 | Yes | ||
| 17 | ZAP70 | 14271 4042 | 2886 | 0.219 | 0.6481 | No | ||
| 18 | JAK2 | 23893 9197 3706 | 3607 | 0.130 | 0.6143 | No | ||
| 19 | LAT | 17643 | 3622 | 0.129 | 0.6185 | No | ||
| 20 | MAPK9 | 1233 20903 1383 | 4094 | 0.096 | 0.5968 | No | ||
| 21 | RAC3 | 20561 | 4683 | 0.069 | 0.5678 | No | ||
| 22 | FOSL1 | 23779 | 4717 | 0.068 | 0.5686 | No | ||
| 23 | PLCG1 | 14753 | 5539 | 0.045 | 0.5262 | No | ||
| 24 | FOSB | 17945 | 7115 | 0.019 | 0.4421 | No | ||
| 25 | FOSL2 | 4733 8978 16878 | 7223 | 0.017 | 0.4370 | No | ||
| 26 | ITK | 4934 | 8021 | 0.007 | 0.3944 | No | ||
| 27 | PRKCQ | 2873 2831 | 9311 | -0.008 | 0.3253 | No | ||
| 28 | SRC | 5507 | 10688 | -0.026 | 0.2523 | No | ||
| 29 | CD4 | 16999 | 12204 | -0.054 | 0.1728 | No | ||
| 30 | MAPK10 | 11169 | 13511 | -0.099 | 0.1063 | No | ||
| 31 | FYN | 3375 3395 20052 | 15886 | -0.398 | -0.0062 | No | ||
| 32 | RAC1 | 16302 | 16377 | -0.547 | -0.0117 | No | ||
| 33 | MAPK8 | 6459 | 16644 | -0.646 | -0.0013 | No | ||
| 34 | JUN | 15832 | 16667 | -0.656 | 0.0226 | No | ||
| 35 | MAP2K4 | 20405 | 16860 | -0.753 | 0.0410 | No | ||
| 36 | LCK | 15746 | 17991 | -1.398 | 0.0336 | No |
